Copper Tripeptide-1

Product Name: (GHK-Cu / Prezatide Copper / Copper Peptide) INCI Name: Copper Tripeptide-1

CAS No.: 89030-95-5

Molecular Formula: C₁₄H₂₂CuN₆O₄

Molecular Weight: 401.91 g/mol

Purity (cosmetic/research grade): ≥98–99.9%

Appearance: Blue to deep blue or purple crystalline powder/solid (characteristic intense blue color due to Cu²⁺ coordination)

Key Features & Properties

Naturally occurring copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK), first isolated from human plasma in 1973
Strong copper chelation — high-affinity binding (log K ≈ 16.4) that delivers bioavailable, non-toxic Cu²⁺ while suppressing redox activity
Intense blue color — visual marker of complex formation and purity
Highly water-soluble — ideal for aqueous serums, creams, and lotions
Stable in formulations at pH 5.5–7.0; sensitive to strong acids/bases and certain chelators
Odor: Mild, characteristic (often acetic-like in powder form)
Hygroscopic — store in airtight containers under cool, dry conditions

Prime Applications & Benefits

Gold-standard anti-aging active in premium skincare — stimulates collagen I & IV, elastin, glycosaminoglycans, and proteoglycan synthesis in fibroblasts
Promotes skin regeneration — accelerates wound healing, improves barrier function, reduces inflammation, and provides antioxidant protection
Visible results — tightens loose skin, reverses thinning, smooths fine lines/wrinkles, enhances firmness/elasticity, and improves overall skin clarity & density
Hair care powerhouse — enlarges hair follicles, increases hair growth/thickness; widely used in scalp serums and anti-hair loss products
Versatile cosmetic ingredient — found in serums, creams, eye treatments, masks, and hair products at typical use levels of 0.05–1.0%
Backed by decades of research — modulates thousands of genes toward youthful expression patterns; outperforms vitamin C and some retinoids in collagen stimulation in certain studies

Storage & Handling Recommendation: Store in a cool (2–8 °C), dry place, protected from light and moisture. Use airtight, light-resistant containers. For best stability in final formulations, maintain pH 5.5–7.0 and avoid strong chelators or extreme conditions.

Discover the legendary “blue copper peptide” — the pioneering regenerative ingredient discovered over 50 years ago that continues to redefine modern anti-aging and skin repair cosmetics!

Here are representative molecular structure diagrams and visuals of Copper Tripeptide-1 (GHK-Cu), the iconic blue copper peptide complex: